Article
VH3 family antibodies bind domain D of staphylococcal protein A.
Journal of immunology (Baltimore, Md. : 1950) - 15 Jun 1995
Roben P W, Salem A N, Silverman G J
Abstract excerpt
Staphylococcal protein A (SpA) is a 45-kDa bacterial membrane protein that can interact with either Fc gamma, a constant region portion of IgG, or with the Fab portion that also mediates conventional Ag binding. In recent reports, SpA has been shown to specifically interact with Fab derived from the VH3 family and is little affected by VH CDR3, JH, or light chain usage. To identify a site on SpA responsible for...
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