Article
Lung fibroblast alpha-smooth muscle actin expression and contractile phenotype in bleomycin-induced pulmonary fibrosis.
The American journal of pathology - 1 Feb 1996
Zhang H Y, Gharaee-Kermani M, Zhang K, Karmiol S, Phan S H
Abstract excerpt
The emergence of the myofibroblast phenotype (characterized by alpha-smooth muscle actin expression) in wound healing and in tissues undergoing fibrosis is thought to be responsible for the increased contractility of the affected tissues. In bleomycin-induced pulmonary fibrosis, the myofibroblast...
Topics
- Actins
- Animals
- Base Sequence
- Bleomycin
- Cell Count
- Cells, Cultured
- Collagen
- Culture Media
- Fibroblasts
- Gels
- Lung
- Male
- Molecular Sequence Data
- Muscle, Smooth
- Phenotype
- Pulmonary Fibrosis
- Rats
- Rats, Inbred F344