Article
Myofibroblast Markers and Microscopy Detection Methods in Cell Culture and Histology.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2021
Younesi Fereshteh S, Son Dong Ok, Firmino Joao, Hinz Boris
Abstract excerpt
The identification of myofibroblasts is essential for mechanistic in vitro studies, cell-based drug tests, and to assess the level of fibrosis in experimental animal or human fibrosis. The name myo-fibroblast was chosen in 1971 to express that the formation of contractile features-stress fibers is the essential criterion to define these cells. Additional neo-expression of α-smooth muscle actin (α-SMA) in stress...
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