Article
Heterogeneity of myofibroblast phenotypic features: an example of fibroblastic cell plasticity.
Virchows Archiv : an international journal of pathology - 1 Jan 1994
Schmitt-Gräff A, Desmoulière A, Gabbiani G
Abstract excerpt
Granulation tissue fibroblasts (myofibroblasts) develop several ultrastructural and biochemical features of smooth muscle (SM) cells, including the presence of microfilament bundles and the expression of alpha-SM actin, the actin isoform present in SM cells and myoepithelial cells and particularly abundant in vascular SM cells. Myofibroblasts have been suggested to play a role in wound contraction and in...
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