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Article

Heterogeneity of myofibroblast phenotypic features: an example of fibroblastic cell plasticity.

Virchows Archiv : an international journal of pathology - 1 Jan 1994

Schmitt-Gräff A, Desmoulière A, Gabbiani G

Abstract excerpt

Granulation tissue fibroblasts (myofibroblasts) develop several ultrastructural and biochemical features of smooth muscle (SM) cells, including the presence of microfilament bundles and the expression of alpha-SM actin, the actin isoform present in SM cells and myoepithelial cells and particularly abundant in vascular SM cells. Myofibroblasts have been suggested to play a role in wound contraction and in...

Topics

Animals
Cell Line
Cicatrix
Fibroblasts
Humans
Microscopy, Electron
Muscle, Smooth
Neoplasms
Phenotype
Reference Values
Wound Healing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 7921410
DOI: 10.1007/BF00193944

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7921410-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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