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Article

Bradykinin differentiates human lung fibroblasts to a myofibroblast phenotype via the B2 receptor.

The Journal of allergy and clinical immunology - 1 Dec 2005

Vancheri Carlo, Gili Elisa, Failla Marco, Mastruzzo Claudio, Salinaro Elisa Trovato, Lofurno Debora, Pistorio Maria P, La Rosa Cristina, Caruso Massimo, Crimi Nunzio

Abstract excerpt

BACKGROUND: The identification of factors mediating the transition of lung fibroblasts into myofibroblasts is considered fundamental in the comprehension of abnormal reparative processes. Bradykinin, a mediator known for its proinflammatory action, is able to induce cytokine production and contractility in fibroblast cultures. OBJECTIVES: In this study the ability of bradykinin to drive fibroblast into a...

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Source

Identifiers

PMID: 16337452
DOI: 10.1016/j.jaci.2005.09.025

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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