Article
A second-generation linkage map of the human genome.
Nature - 29 Oct 1992
Weissenbach J, Gyapay G, Dib C, Vignal A, Morissette J, Millasseau P, Vaysseix G, Lathrop M
Abstract excerpt
A linkage map of the human genome has been constructed based on the segregation analysis of 814 newly characterized polymorphic loci containing short tracts of (C-A)n repeats in a panel of DNAs from eight large families. Statistical linkage analysis placed 813 of the markers into 23 linkage groups corresponding to the 22 autosomes and the X chromosome; 605 show a heterozygosity above 0.7 and 553 could be ordered...
Topics
- Chromosome Mapping
- Chromosomes, Human
- DNA
- Gene Library
- Genetic Linkage
- Genetic Markers
- Genome, Human
- Genotype
- Heterozygote
- Humans
- Polymerase Chain Reaction
- Repetitive Sequences, Nucleic Acid