Article
Gene expression, polarising activity and skeletal patterning in reaggregated hind limb mesenchyme.
Development (Cambridge, England) - 1 Dec 1995
Hardy A, Richardson M K, Francis-West P H, Rodriguez C, Izpisúa-Belmonte J C, Duprez D, Wolpert L
Abstract excerpt
The developing chick limb has two major signalling centres; the apical ectodermal ridge maintains expression of several important genes and outgrowth of the limb, and the polarising region specifies the pattern of skeletal elements along the anteroposterior axis. We have used reaggregated leg gra...
Topics
- Animals
- Bone and Bones
- Chick Embryo
- Gene Expression
- Genes, Homeobox
- Hedgehog Proteins
- Hindlimb
- Mesoderm
- Morphogenesis
- Phenotype
- Proteins
- Trans-Activators
- Transforming Growth Factor beta