Article
Expression of genes encoding bone morphogenetic proteins and sonic hedgehog in talpid (ta3) limb buds: their relationships in the signalling cascade involved in limb patterning.
Developmental dynamics : an official publication of the American Association of Anatomists - 1 Jun 1995
Francis-West P H, Robertson K E, Ede D A, Rodriguez C, Izpisúa-Belmonte J C, Houston B, Burt D W, Gribbin C, Brickell P M, Tickle C
Abstract excerpt
The chicken mutant talpid3 (ta3) has polydactylous limbs with up to 7-8 morphologically similar digits. This lack of antero-posterior polarity in digit pattern is correlated with symmetrical expression of genes of the HoxD complex. We determined the distribution of polarizing activity in limb bud...
Topics
- Animals
- Bone Morphogenetic Protein 7
- Bone Morphogenetic Proteins
- Chick Embryo
- Chromosome Mapping
- Embryonic and Fetal Development
- Extremities
- Fibroblast Growth Factor 4
- Fibroblast Growth Factors
- Gene Expression
- Genes
- Hedgehog Proteins