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Article

Repression of the alpha-fetoprotein gene promoter by progesterone and chimeric receptors in the presence of hormones and antihormones.

Molecular and cellular biology - 1 Sept 1990

Turcotte B, Meyer M E, Bocquel M T, Bélanger L, Chambon P

Abstract excerpt

Using transient transfection assays, we showed that repression of the alpha-fetoprotein promoter by intact and deletion mutants of the progesterone receptor and by chimeric progesterone/glucocorticoid-estrogen receptors in the presence of their cognate hormones was closely correlated with their ability to bind to a progesterone/glucocorticoid-responsive element. This negative regulation was also observed in the...

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Identifiers

PMID: 1697036
DOI: 10.1128/mcb.10.9.5002-5006.1990
PMCID: PMC361135

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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