Article
The polymerase chain reaction with sequence specific primers for the detection of the factor V mutation associated with activated protein C resistance.
Thrombosis and haemostasis - 1 Sept 1995
Kirschbaum N E, Foster P A
Abstract excerpt
The prevalence of the Factor V (FV) mutation associated with activated protein C resistance (FV Leiden) and its significance as a genetic risk factor for venous thrombosis have necessitated the development of a simple, rapid, and accurate assay for its detection. The polymerase chain reaction wit...
Topics
- Base Sequence
- DNA Primers
- Drug Resistance
- Factor V
- Genome, Human
- Humans
- Molecular Sequence Data
- Mutation
- Polymerase Chain Reaction
- Predictive Value of Tests
- Protein C
- Reproducibility of Results