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The polymerase chain reaction with sequence specific primers for the detection of the factor V mutation associated with activated protein C resistance.

Thrombosis and haemostasis - 1 Sept 1995

Kirschbaum N E, Foster P A

Abstract excerpt

The prevalence of the Factor V (FV) mutation associated with activated protein C resistance (FV Leiden) and its significance as a genetic risk factor for venous thrombosis have necessitated the development of a simple, rapid, and accurate assay for its detection. The polymerase chain reaction with sequence specific primers (PCR-SSP) provides a powerful technique for the discrimination of alleles resulting from...

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PMID: 8571314

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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