Allele-specific PCR amplification of factor V Leiden to identify patients at risk for thromboembolism.

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Article

Allele-specific PCR amplification of factor V Leiden to identify patients at risk for thromboembolism.

Beitrage zur Infusionstherapie und Transfusionsmedizin = Contributions to infusion therapy and transfusion medicine - 1 Jan 1997

Blasczyk R, Wehling J, Ritter M, Neubauer A, Riess H

Abstract excerpt

Resistance to activated protein C is the most common hereditary cause of thrombophilia and is significantly linked to factor V Leiden. We designed primers in order to identify factor V Leiden by allele-specific PCR amplification. Amplification specificity for factor V was ensured by a 3' primer l...

Topics

Alleles
Factor V
Gene Amplification
Genetic Carrier Screening
Homozygote
Humans
Polymerase Chain Reaction
Polymorphism, Restriction Fragment Length
Thromboembolism
Thrombophilia

Source

Open in PubMed

Identifiers

PMID: 9356679

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9356679-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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