Article
Argos transcription is induced by the Drosophila EGF receptor pathway to form an inhibitory feedback loop.
Development (Cambridge, England) - 1 Jan 1996
Golembo M, Schweitzer R, Freeman M, Shilo B Z
Abstract excerpt
Argos is a secreted molecule with an atypical EGF motif. It was recently shown to function as an inhibitor of the signaling triggered by the Drosophila EGF receptor (DER). In this work, we determine the contribution of Argos to the establishment of cell fates in the embryonic ventral ectoderm. Graded activation of DER is essential for patterning the ventral ectoderm. argos mutant embryos show expansion of ventral...
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