Article
Sequential activation of the EGF receptor pathway during Drosophila oogenesis establishes the dorsoventral axis.
Development (Cambridge, England) - 1 Jan 1998
Sapir A, Schweitzer R, Shilo B Z
Abstract excerpt
Previous work has demonstrated a role for the Drosophila EGF receptor (Torpedo/DER) and its ligand, Gurken, in the determination of anterioposterior and dorsoventral axes of the follicle cells and oocyte. The roles of DER in establishing the polarity of the follicle cells were examined further, by following the expression of DER-target genes. One class of genes (e.g. kekon) is induced by the DER pathway at all...
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