Spitz and Wingless, emanating from distinct borders, cooperate to establish cell fate across the Engrailed domain in the Drosophila epidermis.

doi:10.1242/dev.124.23.4837

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Article

Spitz and Wingless, emanating from distinct borders, cooperate to establish cell fate across the Engrailed domain in the Drosophila epidermis.

Development (Cambridge, England) - 1 Dec 1997

O'Keefe L, Dougan S T, Gabay L, Raz E, Shilo B Z, DiNardo S

Abstract excerpt

A key step in development is the establishment of cell type diversity across a cellular field. Segmental patterning within the Drosophila embryonic epidermis is one paradigm for this process. At each parasegment boundary, cells expressing the Wnt family member Wingless confront cells expressing t...

Topics

Animals
Calcium-Calmodulin-Dependent Protein Kinases
DNA-Binding Proteins
Drosophila
Drosophila Proteins
Embryonic Induction
Epidermal Growth Factor
Epidermis
ErbB Receptors
Eye Proteins
Homeodomain Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Membrane Proteins

Mutation

Protein Kinases

Proto-Oncogene Proteins

Receptors, Invertebrate Peptide

Repressor Proteins

Transcription Factors

Source

Open in PubMed

Identifiers

PMID: 9428420
DOI: 10.1242/dev.124.23.4837

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9428420-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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