Article
Mutations modulating the Argos-regulated signaling pathway in Drosophila eye development.
Genetics - 1 Apr 2000
Taguchi A, Sawamoto K, Okano H
Abstract excerpt
Argos is a secreted protein that contains an EGF-like domain and acts as an inhibitor of Drosophila EGF receptor activation. To identify genes that function in the Argos-regulated signaling pathway, we performed a genetic screen for enhancers and suppressors of the eye phenotype caused by the overexpression of argos. As a result, new alleles of known genes encoding components of the EGF receptor pathway, such as...
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