The function of the Drosophila argos gene product in the development of embryonic chordotonal organs.

Abstract excerpt

We characterized the embryonic expression pattern and mutant phenotypes of the Drosophila gene argos, which encodes a secreted protein with an epidermal growth factor motif. The argos null mutation caused an increase in chordotonal (Ch) organs in both the thoracic and the abdominal segments, whereas overexpression of the argos gene resulted in a decrease in these organs. We showed that the argos transcripts are...

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