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Article

Graded Egfr activity patterns the Drosophila eggshell independently of autocrine feedback.

Development (Cambridge, England) - 1 Sept 2009

Boisclair Lachance Jean-François, Fregoso Lomas Mariana, Eleiche Aliaa, Bouchard Kerr Phoenix, Nilson Laura A

Abstract excerpt

The pattern of the Drosophila eggshell is determined by the establishment of a complex and stereotyped pattern of cell fates in the follicular epithelium of the ovary. Localized activation of the Epidermal growth factor receptor (Egfr) is essential for this patterning. Modulation of Egfr pathway activity in time and space determines distinct fates at their appropriate locations, but the details of how Egfr...

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Identifiers

PMID: 19641015
DOI: 10.1242/dev.036103

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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