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Article

Mutant ras promotes haemopoietic cell proliferation or differentiation in a cell-specific manner.

Leukemia - 1 Jan 1996

Maher J, Baker D, Dibb N, Roberts I

Abstract excerpt

The ras gene products play a fundamental role in signal transduction in haemopoiesis. In this study, we have examined the effects of ras upon haemopoietic cell proliferation and differentiation, using two human cell lines which represent different stages of haemopoietic cell maturation. When a mutant H12-ras gene (codon 12: gly-->asp) was expressed in the monoblastic cell line, U937, marked inhibition of growth...

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Identifiers

PMID: 8558943

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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