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Article

Role of Ras signaling in erythroid differentiation of mouse fetal liver cells: functional analysis by a flow cytometry-based novel culture system.

Blood - 1 Dec 2003

Zhang Jing, Socolovsky Merav, Gross Alec W, Lodish Harvey F

Abstract excerpt

Ras signaling plays an important role in erythropoiesis. Its function has been extensively studied in erythroid and nonerythroid cell lines as well as in primary erythroblasts, but inconclusive results using conventional erythroid colony-forming unit (CFU-E) assays have been obtained concerning the role of Ras signaling in erythroid differentiation. Here we describe a novel culture system that supports terminal...

Topics

Animals
Cell Culture Techniques
Cell Differentiation
Cell Division
Erythroblasts
Erythropoiesis
Erythropoietin
Fetus
Flow Cytometry
Liver
Mice

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice, Inbred BALB C

Mutation

Signal Transduction

ras Proteins

Source

Identifiers

PMID: 12907435
DOI: 10.1182/blood-2003-05-1479

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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