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Article

Involvement of Wnt-1 in the formation of the mes/metencephalic boundary.

Mechanisms of development - 1 Sept 1995

Bally-Cuif L, Cholley B, Wassef M

Abstract excerpt

Wnt-1, a putative signaling molecule, is required before the 7 somite stage (E8.5) for the development of midbrain structures in the mouse. We show here that Wnt-1 is also needed for the formation of a boundary between the mesencephalic and metencephalic domains of the neural tube. In embryos homozygous for the Wnt-1sw allele, mesencephalic and metencephalic markers fail to segregate and the establishment of a...

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Identifiers

PMID: 8555108
DOI: 10.1016/0925-4773(95)00421-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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