Article
Engrailed defines the position of dorsal di-mesencephalic boundary by repressing diencephalic fate.
Development (Cambridge, England) - 1 Nov 1999
Araki I, Nakamura H
Abstract excerpt
Regionalization of a simple neural tube is a fundamental event during the development of central nervous system. To analyze in vivo the molecular mechanisms underlying the development of mesencephalon, we ectopically expressed Engrailed, which is expressed in developing mesencephalon, in the brain of chick embryos by in ovo electroporation. Misexpression of Engrailed caused a rostral shift of the di-mesencephalic...
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