Article
Msx1 is required for dorsal diencephalon patterning.
Development (Cambridge, England) - 1 Sept 2003
Bach Antoine, Lallemand Yvan, Nicola Marie-Anne, Ramos Casto, Mathis Luc, Maufras Mathilde, Robert Benoît
Abstract excerpt
The dorsal midline of the neural tube has recently emerged as a major signaling center for dorsoventral patterning. Msx genes are expressed at the dorsal midline, although their function at this site remains unknown. Using Msx1(nlacZ) mutant mice, we show that the normal expression domain of Msx1 is interrupted in the pretectum of mutant embryos. Morphological and gene expression data further indicate that a...
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