Article
Evidence that FGF8 signalling from the midbrain-hindbrain junction regulates growth and polarity in the developing midbrain.
Development (Cambridge, England) - 1 Mar 1997
Lee S M, Danielian P S, Fritzsch B, McMahon A P
Abstract excerpt
The developing vertebrate mesencephalon shows a rostrocaudal gradient in the expression of a number of molecular markers and in the cytoarchitectonic differentiation of the tectum, where cells cease proliferating and differentiate in a rostral to caudal progression. Tissue grafting experiments ha...
Topics
- Animals
- Body Patterning
- Brain
- DNA-Binding Proteins
- Diencephalon
- Fibroblast Growth Factor 8
- Fibroblast Growth Factors
- Growth Substances
- Homeodomain Proteins
- Mesencephalon
- Mice
- Mice, Transgenic
- Mutagenesis
- Nerve Tissue Proteins
- Nuclear Proteins
- Phenotype
- Pons
- Proto-Oncogene Proteins