Article
Pax-6 functions in boundary formation and axon guidance in the embryonic mouse forebrain.
Development (Cambridge, England) - 1 May 1997
Mastick G S, Davis N M, Andrew G L, Easter S S
Abstract excerpt
The Pax-6 gene encodes a transcription factor that is expressed in regionally restricted patterns in the developing brain and eye. Here we describe Pax-6 expression in the early forebrain (prosencephalon) on embryonic day 9.5 (E9.5) to E10.5 using both whole-mount in situ hybridization and antibo...
Topics
- Animals
- Axons
- Body Patterning
- Brain
- DNA-Binding Proteins
- Eye Proteins
- Gene Expression Regulation, Developmental
- Genotype
- Homeodomain Proteins
- LIM-Homeodomain Proteins
- Mesencephalon
- Mice
- Mutation
- Neurons
- PAX3 Transcription Factor
- PAX6 Transcription Factor
- Paired Box Transcription Factors
- Prosencephalon