Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Wnt1 and wnt10b function redundantly at the zebrafish midbrain-hindbrain boundary.

Developmental biology - 15 Feb 2003

Lekven Arne C, Buckles Gerri R, Kostakis Nicholas, Moon Randall T

Abstract excerpt

Wnt signals have been shown to be involved in multiple steps of vertebrate neural patterning, yet the relative contributions of individual Wnts to the process of brain regionalization is poorly understood. Wnt1 has been shown in the mouse to be required for the formation of the midbrain and the anterior hindbrain, but this function of wnt1 has not been explored in other model systems. Further, wnt1 is part of a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Enhancer Elements, Genetic
Share to Fibroblast Growth Factor 8

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Fibroblast Growth Factors

Share to Mesencephalon

Share to PAX2 Transcription Factor

Share to Rhombencephalon

Share to Wnt Proteins

Share to Wnt1 Protein

Source

Identifiers

PMID: 12591239
DOI: 10.1016/s0012-1606(02)00044-1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Wnt1 and wnt10b function redundantly at the zebrafish midbrain-hindbrain boundary.PMID 12591239Read ↗

Lmx1b is essential for Fgf8 and Wnt1 expression in the isthmic organizer during tectum and cerebellum development in mice.Semantic proximity Read ↗

Zebrafish wnt8 and wnt8b share a common activity but are involved in distinct developmental pathways.Semantic proximity Read ↗

Involvement of Wnt-1 in the formation of the mes/metencephalic boundary.Semantic proximity Read ↗

Loss of Wnt8b has no overt effect on hippocampus development but leads to altered Wnt gene expression levels in dorsomedial telencephalon.Semantic proximity Read ↗

Rhombomere boundaries are Wnt signaling centers that regulate metameric patterning in the zebrafish hindbrain.Semantic proximity Read ↗

Zebrafish gbx1 refines the midbrain-hindbrain boundary border and mediates the Wnt8 posteriorization signal.Semantic proximity Read ↗

Genetic dissection of midbrain dopamine neuron development in vivo.Semantic proximity Read ↗

Neural patterning and CNS functions of Wnt in zebrafish.Semantic proximity Read ↗

Ectopic Wnt/beta-catenin signaling induces neurogenesis in the spinal cord and hindbrain floor plate.Semantic proximity Read ↗

Zebrafish wnt4b expression in the floor plate is altered in sonic hedgehog and gli-2 mutants.Semantic proximity Read ↗

A 5.5-kb enhancer is both necessary and sufficient for regulation of Wnt-1 transcription in vivo.Semantic proximity Read ↗

Zebrafish wnt8 encodes two wnt8 proteins on a bicistronic transcript and is required for mesoderm and neurectoderm patterning.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.