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Article

Influence of apolipoprotein E genotype on the transmission of Alzheimer disease in a community-based sample.

American journal of human genetics - 1 Jan 1996

Jarvik G, Larson E B, Goddard K, Schellenberg G D, Wijsman E M

Abstract excerpt

The epsilon 4 allele of the apolipoprotein E locus (APOE) has been found to be an important predictor of Alzheimer disease (AD). However, linkage analysis has not clarified the role of APOE in the transmission of AD. The results of the current study provide evidence that the pattern of transmission of memory disorders differs in nuclear families in which the AD-affected proband did carry an epsilon 4 allele...

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Identifiers

PMID: 8554056
PMCID: PMC1914964

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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