Article
Mutations in an exposed domain of Sindbis virus capsid protein result in the production of noninfectious virions and morphological variants.
Virology - 1 Jul 1994
Lee H, Brown D T
Abstract excerpt
A critical event in the process of Sindbis virus assembly is the interaction of the virus nucleocapsid with the target membrane which has been modified by virus envelope glycoproteins. A specific association between the endodomain of the pE2/E2 glycoprotein and an unidentified domain in the capsid protein is responsible for this association. We have examined the nature of this association by the production of a...
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