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Article

The configuration of Sindbis virus envelope proteins is stabilized by the nucleocapsid protein.

Virology - 1 Oct 1994

Lee H, Ricker P D, Brown D T

Abstract excerpt

We have previously provided evidence that a strong and precise interaction of the Sindbis virus nucleocapsid with the cytoplasmic tail of E2 is critical for the function of the mature virion and that changes in this association may affect infectivity (21). In this study, we examined the effects of temperature-sensitive defects in capsid protein on virus infectivity and glycoprotein function. The two Sindbis virus...

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Identifiers

PMID: 8091681
DOI: 10.1006/viro.1994.1557

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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The configuration of Sindbis virus envelope proteins is stabilized by the nucleocapsid protein.PMID 8091681Read ↗

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Molecular Links between the E2 Envelope Glycoprotein and Nucleocapsid Core in Sindbis VirusSemantic proximity Read ↗

Single amino acid insertions at the junction of the sindbis virus E2 transmembrane domain and endodomain disrupt virus envelopment and alter infectivity.Semantic proximity Read ↗

Site-directed mutations in Sindbis virus E2 glycoprotein's cytoplasmic domain and the 6K protein lead to similar defects in virus assembly and budding.Semantic proximity Read ↗

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