Article
Location and role of free cysteinyl residues in the Sindbis virus E1 and E2 glycoproteins.
Journal of virology - 1 Jun 2007
Whitehurst Christopher B, Soderblom Erik J, West Michelle L, Hernandez Raquel, Goshe Michael B, Brown Dennis T
Abstract excerpt
Sindbis virus is a single-stranded positive-sense RNA virus. It is composed of 240 copies of three structural proteins: E1, E2, and capsid. These proteins form a mature virus particle composed of two nested T=4 icosahedral shells. A complex network of disulfide bonds in the E1 and E2 glycoproteins is developed through a series of structural intermediates as virus maturation occurs (M. Mulvey and D. T. Brown, J....
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