Article
Absence of ras gene mutations in early gastric carcinomas.
Gut - 1 Dec 1995
Craanen M E, Blok P, Top B, Boerrigter L, Dekker W, Offerhaus G J, Tytgat G N, Rodenhuis S
Abstract excerpt
The aims of this study were to assess the prevalence and type of activating point mutations at codons 12, 13, and 61 of the Ki-, Ha-, and N-ras genes in a series of early gastric carcinomas in white patients and to correlate these ras gene mutations, if any, with the histological type (Lauren cla...
Topics
- Base Sequence
- Genes, ras
- Humans
- Immunoblotting
- Molecular Sequence Data
- Mutation
- Neoplasm Invasiveness
- Polymerase Chain Reaction
- Polymorphism, Restriction Fragment Length
- Stomach Neoplasms