Article
No evidence for point mutations in codons 12, 13, and 61 of the ras gene in a high-incidence area for esophageal and gastric cancers.
Cancer research - 15 Aug 1990
Victor T, Du Toit R, Jordaan A M, Bester A J, van Helden P D
Abstract excerpt
The molecular mechanisms underlying the induction of esophageal and gastric cancer are not yet understood. It is possible that different etiological factors from geographically distinct areas play a role in the onset of these cancers. Twenty-seven primary esophageal and 11 gastric cancers origina...
Topics
- Base Sequence
- Carcinoma, Squamous Cell
- Codon
- DNA-Directed DNA Polymerase
- Esophageal Neoplasms
- Genes, ras
- Humans
- Incidence
- Molecular Sequence Data
- Mutation
- Nucleic Acid Hybridization
- Oligonucleotide Probes
- Polymerase Chain Reaction
- RNA, Messenger
- South Africa
- Stomach Neoplasms
- Taq Polymerase