Article
Discordant patterns of linkage disequilibrium of the peptide-transporter loci within the HLA class II region.
American journal of human genetics - 1 Dec 1995
Klitz W, Stephens J C, Grote M, Carrington M
Abstract excerpt
Disequilibrium between genetic markers is expected to decline monotonically with recombinational map distance. We present evidence from the HLA class II region that seems to violate this principle. Pairwise disequilibrium values were calculated from six loci ranging in physical separation from 15 kb to 550 kb. The histocompatibility loci DRB1, DQA1, and DQB1, located on the distal end of the class II region,...
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