Sampling variance and distribution of the D' measure of overall gametic disequilibrium between multiallelic loci.

doi:10.1017/S0003480001008697

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Article

Sampling variance and distribution of the D' measure of overall gametic disequilibrium between multiallelic loci.

Annals of human genetics - 1 Jul 2001

Zapata C, Carollo C, Rodriguez S

Abstract excerpt

The development of the theory of estimation of gametic disequilibrium for multiallelic systems is particularly necessary, since a large number of the genetic markers available at present are highly polymorphic multiallelic systems. The D' coefficient is one of the most commonly used measures of the extent of overall disequilibrium between all possible pairs of alleles at two multiallelic loci. Nevertheless, the...

Topics

Alleles
Analysis of Variance
Computer Simulation
Gene Frequency
Germ Cells
Haplotypes
Humans
Linkage Disequilibrium
Microsatellite Repeats
Models, Genetic
Monte Carlo Method
Sampling Studies
Spain

Source

Open in PubMed

Identifiers

PMID: 11592929
DOI: 10.1017/S0003480001008697

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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