Article
Genetic variability and linkage disequilibrium within the HLA-DP region: analysis of 15 different populations.
Tissue antigens - 1 May 2001
Begovich A B, Moonsamy P V, Mack S J, Barcellos L F, Steiner L L, Grams S, Suraj-Baker V, Hollenbach J, Trachtenberg E, Louie L, Zimmerman P, Hill A V, Stoneking M, Sasazuki T, Konenkov V I, Sartakova M L, Titanji V P, Rickards O, Klitz W
Abstract excerpt
In order to understand the forces governing the evolution of the genetic diversity in the HLA-DP molecule, polymerase chain reaction (PCR)-based methods were used to characterize genetic variation at the DPA1 and DPB1 loci encoding this heterodimer on 2,807 chromosomes from 15 different populations including individuals of African, Asian, Amerindian, Indian and European origin. These ethnically diverse samples...
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