Article
A scan for linkage disequilibrium across the human genome.
Genetics - 1 Aug 1999
Huttley G A, Smith M W, Carrington M, O'Brien S J
Abstract excerpt
Linkage disequilibrium (LD), the tendency for alleles of linked loci to co-occur nonrandomly on chromosomal haplotypes, is an increasingly useful phenomenon for (1) revealing historic perturbation of populations including founder effects, admixture, or incomplete selective sweeps; (2) estimating elapsed time since such events based on time-dependent decay of LD; and (3) disease and phenotype mapping, particularly...
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