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Article

Functional cooperation between CREM and GCNF directs gene expression in haploid male germ cells

13 Jan 2010

Abstract excerpt

Cellular differentiation and development of germ cells critically depend on a coordinated activation and repression of specific genes. The underlying regulation mechanisms, however, still lack a lot of understanding. Here, we describe that both the testis-specific transcriptional activator CREMtau (cAMP response element modulator tau) and the repressor GCNF (germ cell nuclear factor) have an overlapping binding...

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PMID: 20071744
DOI: 10.1093/nar/gkp1220

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