Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

GABPα Binding to Overlapping ETS and CRE DNA Motifs Is Enhanced by CREB1: Custom DNA Microarrays.

G3 (Bethesda, Md.) - 16 Jul 2015

He Ximiao, Syed Khund Sayeed, Tillo Desiree, Mann Ishminder, Weirauch Matthew T, Vinson Charles

Abstract excerpt

To achieve proper spatiotemporal control of gene expression, transcription factors cooperatively assemble onto specific DNA sequences. The ETS domain protein monomer of GABPα and the B-ZIP domain protein dimer of CREB1 cooperatively bind DNA only when the ETS ((C)/GCGGAA GT: ) and CRE ( GT: GACGTCAC) motifs overlap precisely, producing the ETS↔CRE motif ((C)/GCGGAA GT: GACGTCAC). We designed a Protein Binding...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Binding Sites
Share to Cyclic AMP Response Element-Binding Protein

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetic Loci

Share to Nucleotide Motifs

Share to Oligonucleotide Array Sequence Analysis

Share to Protein Binding

Share to Proto-Oncogene Proteins c-ets

Share to Recombinant Fusion Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 26185160
DOI: 10.1534/g3.115.020248
PMCID: PMC4555227

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

GABPα Binding to Overlapping ETS and CRE DNA Motifs Is Enhanced by CREB1: Custom DNA Microarrays.PMID 26185160Read ↗

BART: a transcription factor prediction tool with query gene sets or epigenomic profilesSemantic proximity Read ↗

<b>MARGE:</b> Mutation Analysis for Regulatory Genomic ElementsSemantic proximity Read ↗

Multiplexed dissection of a model human transcription factor binding site architectureSemantic proximity Read ↗

Genome‐wide analysis of ETS‐family DNA‐binding in vitro and in vivoSemantic proximity Read ↗

EBF contains a novel zinc coordination motif and multiple dimerization and transcriptional activation domains.Semantic proximity Read ↗

Dimerization specificity of the leucine zipper-containing bZIP motif on DNA binding: prediction and rational design.Semantic proximity Read ↗

Exploring the effects of polymorphisms on cis-regulatory signal transduction response.Semantic proximity Read ↗

CGGBP1 from higher amniotes restricts cytosine methylation and drives a GC-bias in transcription factor binding sites at repressed promotersSemantic proximity Read ↗

Basic leucine zipper transcription factor Hac1 binds DNA in two distinct modes as revealed by microfluidic analyses.Semantic proximity Read ↗

A quantitative dissection of the DNA-binding properties of pathogenic GATA1 mutants.Semantic proximity Read ↗

The Epstein-Barr Virus B-ZIP Protein Zta Recognizes Specific DNA Sequences Containing 5-Methylcytosine and 5-Hydroxymethylcytosine.Semantic proximity Read ↗

Amino acid residues in the beta3 strand and subsequent loop of the conserved ETS domain that mediate basic leucine zipper (bZIP) recruitment and potentially distinguish functional attributes of Ets proteins.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.