Article
Hepatitis B virus X protein transactivates the long terminal repeats of human immunodeficiency virus types 1 and 2.
Journal of virology - 1 Jun 1990
Levrero M, Balsano C, Natoli G, Avantaggiati M L, Elfassi E
Abstract excerpt
The X gene product of the hepatitis B virus (HBV) has been expressed transiently in HepG2 cells, and the 17-kilodalton protein has been detected by Western (immuno-) blot analysis. Cotransfection of the X gene with the long terminal repeat of human immunodeficiency virus type 1 or 2 results in a stimulation of long terminal repeat-directed expression that is higher than the X-induced stimulation of the HBV...
Topics
- Blotting, Western
- Cell Line
- Chromosome Deletion
- Enhancer Elements, Genetic
- Genes, Viral
- HIV-1
- HIV-2
- Hepatitis B virus
- Humans
- Mutation
- Plasmids
- Repetitive Sequences, Nucleic Acid
