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Article

Distinguishing second primary tumors from lung metastases in patients with head and neck squamous cell carcinoma.

Journal of the National Cancer Institute - 1 Jul 1998

Leong P P, Rezai B, Koch W M, Reed A, Eisele D, Lee D J, Sidransky D, Jen J, Westra W H

Abstract excerpt

BACKGROUND: In patients with head and neck squamous cell carcinoma (HNSCC), a squamous cell carcinoma (SCC) in the lung represents either another primary tumor or a metastasis. This distinction greatly influences patient prognosis and could guide treatment strategies, but the nature of a solitary lung nodule is often difficult to discern by use of standard clinical and histologic parameters. Comparison of genetic...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 9665144
DOI: 10.1093/jnci/90.13.972

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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