Specific RNA residue interactions required for enzymatic functions of Tetrahymena telomerase.

doi:10.1128/MCB.16.1.66

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Article

Specific RNA residue interactions required for enzymatic functions of Tetrahymena telomerase.

Molecular and cellular biology - 1 Jan 1996

Gilley D, Blackburn E H

Abstract excerpt

The ribonucleoprotein enzyme telomerase is a specialized reverse transcriptase that synthesizes telomeric DNA by copying a template sequence within the telomerase RNA. Here we analyze the actions of telomerase from Tetrahymena thermophila assembled in vivo with mutated or wild-type telomerase RNA...

Topics

Animals
Base Composition
Base Sequence
Binding Sites
DNA Primers
DNA, Protozoan
Molecular Sequence Data
Mutation
Phenotype
RNA, Protozoan
Telomerase
Tetrahymena thermophila

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