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Article

Extragenic suppressors of mutations in the cytoplasmic C terminus of SEC63 define five genes in Saccharomyces cerevisiae.

Genetics - 1 May 1993

Nelson M K, Kurihara T, Silver P A

Abstract excerpt

Mutations in the SEC63 gene of Saccharomyces cerevisiae affect both nuclear protein localization and translocation of proteins into the endoplasmic reticulum. We now report the isolation of suppressors of sec63-101 (formerly npl1-1), a temperature-sensitive allele of SEC63. Five complementation g...

Topics

Alleles
Amino Acid Sequence
Base Sequence
Chromosome Mapping
Cloning, Molecular
DNA, Fungal
Fungal Proteins
Genes, Fungal
Glycerol
Molecular Sequence Data
Mutation
Nuclear Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Saccharomyces cerevisiae

Suppression, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 8514125
DOI: 10.1093/genetics/134.1.159
PMCID: PMC1205419

Genes

SEC63
SEC62

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8514125-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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