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Article

A novel gene, spp91-1, suppresses the splicing defect and the pre-mRNA nuclear export in the prp9-1 mutant.

The EMBO journal - 1 Sept 1992

Chapon C, Legrain P

Abstract excerpt

Processing and export of nuclear pre-mRNA are believed to be competing processes in the nucleus. In order to identify factors which are involved in these processes, we isolated suppressors that relieve the growth defect of a prp9-1 temperature-sensitive mutant strain of Saccharomyces cerevisiae. The prp9-1 mutation was previously shown to abolish splicing and to target pre-mRNA to the cytoplasm. One of the...

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Identifiers

PMID: 1505518
DOI: 10.1002/j.1460-2075.1992.tb05406.x
PMCID: PMC556862

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