Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Nuclear transport defects and nuclear envelope alterations are associated with mutation of the Saccharomyces cerevisiae NPL4 gene.

Molecular biology of the cell - 1 Nov 1996

DeHoratius C, Silver P A

Abstract excerpt

To identify components involved in nuclear protein import, we used a genetic selection to isolate mutants that mislocalized a nuclear-targeted protein. We identified temperature-sensitive mutants that accumulated several different nuclear proteins in the cytoplasm when shifted to the semipermissive temperature of 30 degrees C; these were termed npl (nuclear protein localization) mutants. We now present the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Cloning, Molecular
Share to Genes, Fungal

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Molecular Sequence Data

Share to Mutation

Share to RNA, Messenger

Share to Saccharomyces cerevisiae

Share to Temperature

Source

Open in PubMed Open full text

Identifiers

PMID: 8930904
DOI: 10.1091/mbc.7.11.1835
PMCID: PMC276030

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Nuclear transport defects and nuclear envelope alterations are associated with mutation of the Saccharomyces cerevisiae NPL4 gene.PMID 8930904Read ↗

A mutant nuclear protein with similarity to RNA binding proteins interferes with nuclear import in yeast.Semantic proximity Read ↗

nup1 mutants exhibit pleiotropic defects in nuclear pore complex function.Semantic proximity Read ↗

NNF1 is an essential yeast gene required for proper spindle orientation, nucleolar and nuclear envelope structure and mRNA export.Semantic proximity Read ↗

Nuclear pore complex clustering and nuclear accumulation of poly(A)+ RNA associated with mutation of the Saccharomyces cerevisiae RAT2/NUP120 gene.Semantic proximity Read ↗

The nuclear pore complex.Semantic proximity Read ↗

Approaches to studying subnuclear organization and gene-nuclear pore interactions.Semantic proximity Read ↗

A novel nuclear pore protein Nup133p with distinct roles in poly(A)+ RNA transport and nuclear pore distribution.Semantic proximity Read ↗

Potential RNA binding proteins in Saccharomyces cerevisiae identified as suppressors of temperature-sensitive mutations in NPL3.Semantic proximity Read ↗

Pathogenic mutations in genes encoding nuclear envelope proteins and defective nucleocytoplasmic connections.Semantic proximity Read ↗

Isolation and characterization of new Saccharomyces cerevisiae mutants perturbed in nuclear pore complex assembly.Semantic proximity Read ↗

Nuclear mRNA export requires specific FG nucleoporins for translocation through the nuclear pore complex.Semantic proximity Read ↗

A novel allele of Saccharomyces cerevisiae NDC1 reveals a potential role for the spindle pole body component Ndc1p in nuclear pore assembly.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.