Article
SEN1, a positive effector of tRNA-splicing endonuclease in Saccharomyces cerevisiae.
Molecular and cellular biology - 1 May 1992
DeMarini D J, Winey M, Ursic D, Webb F, Culbertson M R
Abstract excerpt
The SEN1 gene, which is essential for growth in the yeast Saccharomyces cerevisiae, is required for endonucleolytic cleavage of introns from all 10 families of precursor tRNAs. A mutation in SEN1 conferring temperature-sensitive lethality also causes in vivo accumulation of pre-tRNAs and a defici...
Topics
- Alleles
- Amino Acid Sequence
- Base Sequence
- Binding Sites
- Blotting, Northern
- Cloning, Molecular
- DNA Helicases
- DNA Probes
- DNA, Fungal
- Endoribonucleases
- Fungal Proteins
- Genes, Fungal
- Genotype
- Models, Genetic
- Molecular Sequence Data
- Mutation
- Open Reading Frames
- RNA Helicases