Article
Inactivation of the yeast Sen1 protein affects the localization of nucleolar proteins.
Molecular & general genetics : MGG - 20 Dec 1995
Ursic D, DeMarini D J, Culbertson M R
Abstract excerpt
A mutation in the Saccharomyces cerevisiae SEN1 gene causes accumulation of end-matured, intron-containing pre-tRNAs. Cells containing the thermosensitive sen1-1 mutation exhibit reduced tRNA splicing endonuclease activity. However, Sen1p is not the catalytic subunit of this enzyme. We have used...
Topics
- Amino Acid Sequence
- Biological Transport
- Cell Compartmentation
- Cell Nucleolus
- Cell Nucleus
- DNA Helicases
- Fluorescent Antibody Technique, Indirect
- Fungal Proteins
- Genes, Fungal
- HSP70 Heat-Shock Proteins
- Molecular Sequence Data
- Mutation
- Nuclear Proteins
- RNA Helicases
- RNA Ligase (ATP)
- RNA Precursors
- RNA Splicing
- RNA, Transfer