Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Biological characterization of infectious molecular clones derived from a human immunodeficiency virus type-1 isolate with rapid/high replicative capacity.

Virology - 1 Mar 1991

Fredriksson R, Stålhanske P, von Gegerfelt A, Lind B, Aman P, Rassart E, Fenyö E M

Abstract excerpt

In order to molecularly characterize rapidly and slowly replicating HIV-1 variants, molecular clones were obtained from a rapid/high virus isolate. This isolate, 4803, had only been passaged in peripheral blood mononuclear cells (PBMC) prior to cloning. Molecular cloning was done in bacteriophage lambda-dash using high molecular weight DNA of isolate 4803 infected PBMC. Seven recombinant phages were identified....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Line
Share to Cells, Cultured

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cloning, Molecular

Share to Genetic Variation

Share to Lymphocytes

Share to Restriction Mapping

Share to Transfection

Source

Identifiers

PMID: 1704660
DOI: 10.1016/0042-6822(91)90469-r

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Biological characterization of infectious molecular clones derived from a human immunodeficiency virus type-1 isolate with rapid/high replicative capacity.PMID 1704660Read ↗

Cotransfection of HIV-1 molecular clones with restricted cell tropism may yield progeny virus with altered phenotype.Semantic proximity Read ↗

Phenotypic heterogeneity in a panel of infectious molecular human immunodeficiency virus type 1 clones derived from a single individual.Semantic proximity Read ↗

The biological phenotype of HIV-1 is usually retained during and after sexual transmission.Semantic proximity Read ↗

An infectious molecular clone of an unusual macrophage-tropic and highly cytopathic strain of human immunodeficiency virus type 1Semantic proximity Read ↗

Biological phenotype of human immunodeficiency virus type 1 clones at different stages of infection: progression of disease is associated with a shift from monocytotropic to T-cell-tropic virus populationSemantic proximity Read ↗

Characterization of a molecular clone of HIV type 2 infectious for Macaca nemestrina.Semantic proximity Read ↗

Construction and characterization of a full-length HIV-1(92UG001) subtype D infectious molecular clone.Semantic proximity Read ↗

Isolation of human immunodeficiency virus-type 1 (HIV-1) clones with biological and molecular properties of the primary isolate.Semantic proximity Read ↗

Identification of a determinant within the human immunodeficiency virus 1 surface envelope glycoprotein critical for productive infection of primary monocytes.Semantic proximity Read ↗

Changes in growth properties on passage in tissue culture of viruses derived from infectious molecular clones of HIV-1LAI, HIV-1MAL, and HIV-1ELI.Semantic proximity Read ↗

Biological cloning of functionally diverse quasispecies of HIV-1.Semantic proximity Read ↗

Vpr R36w and R77Q Mutations Alter HIV-1 Replication and Cytotoxicity in T LymphocytesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.