Changes in growth properties on passage in tissue culture of viruses derived from infectious molecular clones of HIV-1LAI, HIV-1MAL, and HIV-1ELI.

doi:10.1016/0042-6822(91)90537-l

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Article

Changes in growth properties on passage in tissue culture of viruses derived from infectious molecular clones of HIV-1LAI, HIV-1MAL, and HIV-1ELI.

Virology - 1 Dec 1991

Peden K, Emerman M, Montagnier L

Abstract excerpt

The construction and preliminary biological characterization of three molecular clones of human immunodeficiency virus type 1 (HIV-1) are reported: HIV-1LAI from a French man with AIDS, HIV-1MAL from a Zairian boy with ARC, and HIV-1ELI from a Zairian woman with AIDS. All three sequences were found to code for infectious viruses. Both the host range and the kinetics of infection in CD4+ cells were different for...

Topics

AIDS-Related Complex
Acquired Immunodeficiency Syndrome
Amino Acid Sequence
Base Sequence
CD4-Positive T-Lymphocytes
Cell Line
Cloning, Molecular
Democratic Republic of the Congo
Female
France
Genes, env

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genetic Variation

HIV-1

Humans

Male

Molecular Sequence Data

Monocytes

Proviruses

Source

Open in PubMed

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PMID: 1683726
DOI: 10.1016/0042-6822(91)90537-l

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1683726-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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