Article
Superinfection of defective human immunodeficiency virus type 1 with different subtypes of wild-type virus efficiently produces infectious variants with the initial viral phenotypes by complementation followed by recombination.
Microbes and infection - 1 Apr 2008
Iwabu Yukie, Mizuta Hiroyuki, Kawase Michiko, Kameoka Masanori, Goto Toshiyuki, Ikuta Kazuyoshi
Abstract excerpt
Superinfection rates of human immunodeficiency virus type 1 (HIV-1) have increasingly been leading to more variation in HIV-1, as evidenced by the emergence of circulating recombinant forms (CRFs). We recently reported complementation in a persistently replication-defective subtype B-infected cell clone, L-2, by superinfection with CRF15_01B. The L-2 cells continuously produce immature particles due to a one-base...
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