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Article

Biological cloning of functionally diverse quasispecies of HIV-1.

AIDS research and human retroviruses - 1 Jun 1993

Connor R I, Notermans D W, Mohri H, Cao Y, Ho D D

Abstract excerpt

Twenty putative clones of HIV-1, derived by biological cloning from two different individuals, were characterized in vitro for functional activity and genotypic diversity. Many of the biological clones isolated by this method were genetically distinct, and could be further distinguished by differences in replication kinetics, host cell range, and/or cytopathicity. Our findings indicate that biological cloning by...

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Identifiers

PMID: 8347398
DOI: 10.1089/aid.1993.9.541

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