Article
Proliferation of chicken neuroretina cells induced by v-src, in vitro, depends on activation of the E2F transcription factor.
Oncogene - 3 Jul 1997
Pasteau S, Loiseau L, Brun G
Abstract excerpt
Quiescent chicken or quail retina neuroblasts (NR) can be induced to proliferate actively, in culture, by the v-src oncoprotein. The chE2F-1 transcription factor, a physiological partner of the retinoblastoma gene product, is highly expressed in vivo, in dividing chicken neuroretina cells (CNR)....
Topics
- Animals
- Avian Sarcoma Viruses
- Carrier Proteins
- Cell Cycle
- Cell Cycle Proteins
- Cell Differentiation
- Cell Division
- Cell Transformation, Viral
- Cells, Cultured
- Chickens
- Culture Media, Serum-Free
- DNA-Binding Proteins
- E2F Transcription Factors
- E2F1 Transcription Factor
- Mutation
- Oncogene Protein pp60(v-src)
- Retina
- Retinoblastoma-Binding Protein 1